Title | Pre-pregnancy body mass index, gestational weight gain and postnatal growth in preterm infants. |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Joaquino SMilet, Lee HC, Abrams B |
Journal | J Perinatol |
Volume | 41 |
Issue | 8 |
Pagination | 1825-1834 |
Date Published | 2021 08 |
ISSN | 1476-5543 |
Keywords | Birth Weight, Body Mass Index, Cohort Studies, Female, Gestational Weight Gain, Humans, Infant, Infant, Newborn, Infant, Premature, Overweight, Pregnancy, Risk Factors, Weight Gain |
Abstract | OBJECTIVE: To evaluate associations between pre-pregnancy body mass index (BMI), gestational weight gain (GWG), and postnatal growth in preterm infants. DESIGN: A cohort study of 14,962 births < 32 weeks' gestation. We used multivariable linear regression to assess associations between maternal BMI or GWG (models stratified by BMI) and infant postnatal growth, defined as the difference between discharge and birth weight Z-scores based on Fenton or INTERGROWTH-21st growth charts. RESULT: For BMI, obesity class 2 was positively associated with postnatal growth using the Fenton chart. Using INTERGROWTH-21st, inadequate or excessive GWG in women with underweight or obesity class 3 were associated with postnatal growth in different directions. Excessive GWG in women with normal weight was negatively associated with postnatal growth defined by Fenton. CONCLUSION: Some categories of BMI and GWG were modestly associated with postnatal growth in preterm infants. Results were inconsistent within and between the INTERGROWTH-21st standard and Fenton growth reference. |
DOI | 10.1038/s41372-021-01087-6 |
Alternate Journal | J Perinatol |
PubMed ID | 34012052 |