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Randomized controlled trial of the "WISER" intervention to reduce healthcare worker burnout.

CPQCC Publication
TitleRandomized controlled trial of the "WISER" intervention to reduce healthcare worker burnout.
Publication TypeJournal Article
Year of Publication2021
AuthorsProfit J, Adair KC, Cui X, Mitchell B, Brandon D, Tawfik DS, Rigdon J, Gould JB, Lee HC, Timpson WL, McCaffrey MJ, Davis AS, Pammi M, Matthews M, Stark AR, Papile L-A, Thomas E, Cotten M, Khan A, J Sexton B
JournalJ Perinatol
Date Published2021 09
KeywordsBurnout, Professional, Burnout, Psychological, Female, Health Personnel, Humans, Male

OBJECTIVE: Test web-based implementation for the science of enhancing resilience (WISER) intervention efficacy in reducing healthcare worker (HCW) burnout.

DESIGN: RCT using two cohorts of HCWs of four NICUs each, to improve HCW well-being (primary outcome: burnout). Cohort 1 received WISER while Cohort 2 acted as a waitlist control.

RESULTS: Cohorts were similar, mostly female (83%) and nurses (62%). In Cohorts 1 and 2 respectively, 182 and 299 initiated WISER, 100 and 176 completed 1-month follow-up, and 78 and 146 completed 6-month follow-up. Relative to control, WISER decreased burnout (-5.27 (95% CI: -10.44, -0.10), p = 0.046). Combined adjusted cohort results at 1-month showed that the percentage of HCWs reporting concerning outcomes was significantly decreased for burnout (-6.3% (95%CI: -11.6%, -1.0%); p = 0.008), and secondary outcomes depression (-5.2% (95%CI: -10.8, -0.4); p = 0.022) and work-life integration (-11.8% (95%CI: -17.9, -6.1); p < 0.001). Improvements endured at 6 months.

CONCLUSION: WISER appears to durably improve HCW well-being.


Alternate JournalJ Perinatol
PubMed ID34366432
PubMed Central IDPMC8440181
Grant ListK08 HS027837 / HS / AHRQ HHS / United States
R01 HD084679 / HD / NICHD NIH HHS / United States
K24 HD053771 / HD / NICHD NIH HHS / United States
R01 HD084679-01 / / U.S. Department of Health &amp; Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) /