| Title | Serial aEEG recordings in a cohort of extremely preterm infants: feasibility and safety. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Davis AS, Gantz MG, Do B, Shankaran S, Hamrick SEG, Kennedy KA, Tyson JE, Chalak LF, Laptook AR, Goldstein RF, Hintz SR, Das A, Higgins RD, Ball MB, Hale EC, Van Meurs KP |
| Corporate Authors | Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network |
| Journal | J Perinatol |
| Volume | 35 |
| Issue | 5 |
| Pagination | 373-8 |
| Date Published | 2015 May |
| ISSN | 1476-5543 |
| Keywords | Adult, Brain, Cohort Studies, Electroencephalography, Female, Gestational Age, Humans, Infant, Infant, Extremely Low Birth Weight, Infant, Extremely Premature, Infant, Newborn, Male, Nursing Staff, Hospital, Young Adult |
| Abstract | OBJECTIVE: Amplitude-integrated electroencephalography (aEEG) monitoring is increasing in the neonatal population, but the safety and feasibility of performing aEEG in extremely preterm infants have not been systematically evaluated. STUDY DESIGN: Inborn infants 23(0/7) to 28(6/7) weeks gestation or birth weight 401 to 1000 g were eligible. Serial, 6-h aEEG recordings were obtained from first week of life until 36 weeks postmenstrual age. Adverse events were documented, and surveys evaluated the impact of the aEEGs on routine care. Success of performing aEEGs according to protocol and aEEG quality were assessed. RESULT: A total of 102 infants were enrolled, with 755 recordings performed. 83% of recordings were performed according to schedule, and 96% were without adverse event. Bedside nurses reported no interference with routine care for 89% of recordings. 92% of recordings had acceptable signal quality. CONCLUSION: Serial aEEG monitoring is safe in preterm infants, with few adverse events and general acceptance by nursing staff. |
| DOI | 10.1038/jp.2014.217 |
| Alternate Journal | J Perinatol |
| PubMed ID | 25474559 |
| PubMed Central ID | PMC4414657 |
| Grant List | U10 HD021373 / HD / NICHD NIH HHS / United States U10 HD021385 / HD / NICHD NIH HHS / United States U10 HD027880 / HD / NICHD NIH HHS / United States UG1 HD087229 / HD / NICHD NIH HHS / United States UL1 TR000093 / TR / NCATS NIH HHS / United States U10 HD027904 / HD / NICHD NIH HHS / United States UG1 HD034216 / HD / NICHD NIH HHS / United States UL1 TR000454 / TR / NCATS NIH HHS / United States UL1 TR001117 / TR / NCATS NIH HHS / United States M01 RR000070 / RR / NCRR NIH HHS / United States U10 HD036790 / HD / NICHD NIH HHS / United States UG1 HD068278 / HD / NICHD NIH HHS / United States UL1 TR000371 / TR / NCATS NIH HHS / United States U10 HD040689 / HD / NICHD NIH HHS / United States U10 HD040492 / HD / NICHD NIH HHS / United States UL1 TR001085 / TR / NCATS NIH HHS / United States U10 HD027851 / HD / NICHD NIH HHS / United States UG1 HD021385 / HD / NICHD NIH HHS / United States |
