Title | Utility of prenatal MRI in the evaluation and management of fetal ventriculomegaly. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Katz JA, Chock VY, Davis AS, Blumenfeld YJ, Hahn JS, Barnes P, Barth RA, Rubesova E, Hintz SR |
Journal | J Perinatol |
Volume | 38 |
Issue | 11 |
Pagination | 1444-1452 |
Date Published | 2018 11 |
ISSN | 1476-5543 |
Keywords | Adult, California, Female, Humans, Hydrocephalus, Logistic Models, Magnetic Resonance Imaging, Pregnancy, Prenatal Diagnosis, Retrospective Studies, Ultrasonography, Prenatal |
Abstract | OBJECTIVE: Fetal ventriculomegaly may occur in isolation or as part of a broader syndrome. We aimed to determine the added value of magnetic resonance imaging (MRI) for informing the pre-natal and postnatal care of pregnancies complicated by ventriculomegaly (VM). STUDY DESIGN: Retrospective analysis of all cases of prenatally diagnosed VM referred to the fetal center at Lucile Packard Children's Hospital Stanford 1/1/2009-6/1/2014 were reviewed. Ultrasound (US) and MRI findings were reviewed, and the added yield of MRI evaluated. RESULTS: A total of 91 cases of fetal VM were identified and 74 (81%) underwent MRI. In 62/74 (84%) cases, additional CNS or non-CNS findings, not seen on US, were discovered on MRI, of which 58 were CNS-related. Forty-six (62%) of the additional findings were considered clinically relevant, of which 45 were CNS-related. CONCLUSION: Fetal MRI identifies additional, clinically relevant CNS and non-CNS findings in a majority of cases of VM following initial US. |
DOI | 10.1038/s41372-018-0208-6 |
Alternate Journal | J Perinatol |
PubMed ID | 30158676 |