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Utility of prenatal MRI in the evaluation and management of fetal ventriculomegaly.

CPQCC Publication
TitleUtility of prenatal MRI in the evaluation and management of fetal ventriculomegaly.
Publication TypeJournal Article
Year of Publication2018
AuthorsKatz JA, Chock VY, Davis AS, Blumenfeld YJ, Hahn JS, Barnes P, Barth RA, Rubesova E, Hintz SR
JournalJ Perinatol
Date Published2018 11
KeywordsAdult, California, Female, Humans, Hydrocephalus, Logistic Models, Magnetic Resonance Imaging, Pregnancy, Prenatal Diagnosis, Retrospective Studies, Ultrasonography, Prenatal

OBJECTIVE: Fetal ventriculomegaly may occur in isolation or as part of a broader syndrome. We aimed to determine the added value of magnetic resonance imaging (MRI) for informing the pre-natal and postnatal care of pregnancies complicated by ventriculomegaly (VM).

STUDY DESIGN: Retrospective analysis of all cases of prenatally diagnosed VM referred to the fetal center at Lucile Packard Children's Hospital Stanford 1/1/2009-6/1/2014 were reviewed. Ultrasound (US) and MRI findings were reviewed, and the added yield of MRI evaluated.

RESULTS: A total of 91 cases of fetal VM were identified and 74 (81%) underwent MRI. In 62/74 (84%) cases, additional CNS or non-CNS findings, not seen on US, were discovered on MRI, of which 58 were CNS-related. Forty-six (62%) of the additional findings were considered clinically relevant, of which 45 were CNS-related.

CONCLUSION: Fetal MRI identifies additional, clinically relevant CNS and non-CNS findings in a majority of cases of VM following initial US.

Alternate JournalJ Perinatol
PubMed ID30158676