Revised Authors: Malathi Balasundaram MD, Vinod K. Bhutani, MD, FAAP
CPQCC's Severe Hyperbilirubinemia Prevention Toolkit was recently revised and updated from the 2005 initial version. Neonatal hyperbilirubinemia, a frequent neonatal condition, is generally benign. When untested or unmonitored, safe and effective interventions may be delayed and place an otherwise healthy newborn infant at risk for bilirubin neurotoxicity. Based on extensive research, clinical experience and use of systems-approach, the need for emergency interventions and clinical diagnosis of acute bilirubin encephalopathy as well as kernicterus have become rare and unusual in USA. This toolkit reviews guidelines for the identification and follow-up of term and near tearm infants (> 35 weeks gestation) at risk of hyperbilirubinemia.