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Racial and ethnic disparities in postnatal growth among very low birth weight infants in California.

CPQCC Publication
TitleRacial and ethnic disparities in postnatal growth among very low birth weight infants in California.
Publication TypeJournal Article
Year of Publication2023
AuthorsLee SMin, Sie L, Liu J, Profit J, Main E, Lee HC
JournalJ Perinatol
Volume43
Issue3
Pagination371-377
Date Published2023 Mar
ISSN1476-5543
KeywordsBirth Weight, California, Ethnicity, Female, Health Status Disparities, Humans, Infant, Infant, Newborn, Infant, Very Low Birth Weight, Mothers, Pregnancy
Abstract

OBJECTIVE: To identify racial/ethnic disparities in postnatal growth by year and gestational age among very low birth weight infants.

STUDY DESIGN: Total 37,122 infants, with birth weight 500-1500 g or gestational age 23-34 weeks in the California Perinatal Quality Care Collaborative in 2008-2016. Postnatal growth failure (PGF) was defined as change in weight Z-score from birth to discharge below -1.28. Multivariable regression analysis with birth hospital as random effect was used to estimate odds ratios (OR).

RESULTS: Infants born to Hispanic mothers had highest risk of PGF at 30%, compared to white (24%, OR 1.33), Black (22%, OR 1.50), or Asian/Pacific Islander mothers (23%, OR 1.38). PGF incidence decreased from 2008 (27.4%) to 2016 (22.8%) with differences in trends by race. Each increasing gestational age week was associated with decreasing risk for PGF (OR 0.73, 95% confidence interval 0.72-0.74).

CONCLUSION: Targeted interventions addressing PGF are needed to address disparities.

URLhttps://pubmed.ncbi.nlm.nih.gov/36737570/
DOI10.1038/s41372-023-01612-9
Alternate JournalJ Perinatol
PubMed ID36737570
PubMed Central IDPMC9991910
Grant ListR01 HD084667 / NH / NIH HHS / United States
R01 HD094847 / NH / NIH HHS / United States